People keep asking me about immune supplements and I test them all using my unique methodology. Most of them I have in my lab and have taken myself to experience first hand the relative benefit. Transfer Factor shows about three times the effect of the best supplements I have tried. My experience is consistent with the research literature.
NK CELLS ARE YOUR FIRST AND YOUR LAST LINE OF DEFENSE
Natural Killer (NK) Cells are a type of lethal lymphocyte
Scientists estimate that NK cells make up five to 16 percent of the total number of white blood cells that the body uses to fight infections. Those with defective or absent NK cell activity can contract a wide specturm of diseases, particularly cancers. Results from a number of clinical trials indicate that NK cells can be used to control tumor metastates. The therapeutic uses of NK cell activity will likely increase as their relationships to healthy and diseased cells becomes better known.
Natural Killer (NK) cells –
NK cells were discovered in the 1970’s and are a subset of large granular lymphocytes that are cytotoxic cells. They are called “natural” killers because they, unlike cytotoxic T cells, do not need to recognize a specific antigen before swinging into action. They are capable of spontaneously killing tumor or virus-infected cells. In several immuno-deficiency diseases, including AIDS, natural killer cell function is abnormal. Natural killer cells may also contribute to immuno-regulation by secreting high levels of influential lymphokines. Natural Killer (NK) cells have no immunological memory and are independent of the adaptive immune system, NK cells make up approximately 15% of the human white blood cells. Their specific function is to kill infected and cancerous cells.
Recent research reveals that NK cells are involved in multiple effector, regulatory and developmental activities of the immune system. Research has confirmed that low NK cell activity causes one to be more susceptible to autoimmune diseases such as CFS, viral infections and the development of cancer cells.
Any statement that natural killer (NK) cells play an “important role” in human health is as casual as saying that the brain is important for bodily function. If our brain is not present and active we cannot continue “living”. If our immune system is not armed and working well we will also not continue “living” for very long. NK cell activity is to the immune system, what brain activity is to the body.
Activated NK cells produce a variety of cytokines, including interferons, interlukins, TNF (Tumor Necrosis Factor, hematopietic cell growth factors and other growth factors. There is substantial evidence that indicates the involvement of NK cells in the interactions of the immune system with the neuroendocrine axis. They also appear to be responsible for activities at the interface between the immune system and the reproductive and neurological systems.
NK cell activity and NK cell count are not the same. NK cells may be present in sufficient numbers, but unless they are activated they are ineffective in doing their job. Decreased NK cell activity is linked to the development and progression of many diseases. According to the Center of Disease Control, low NK cell activity is present in all illness. NK cell function appears to be a biologic marker for disease and is an important indicator for declining or improving health.
The following assertion can be made;
if one is suffering from an illness, be it chronic, recurring or acute, the NK cell activity would be below normal. The restoration of NK cell activity to a high normal would be desirable, if not necessary, for recovery. Low NK cell activity begins with stress of some type. When the body is unable to adequately adapt to the environment there is a resulting compromise of body function. Stress comes through loss of sleep, overwork, emotional encounters, lack of exercise, poor nutrition, exposure to toxins, exposure to germs etc.
Excessive stress causes many detrimental changes in the body physiology and particularly the immune system. There is research evidence that there is a relationship between Natural Killer (NK) cell activity and reaction to emotional stress. There is low NK cell activity in individuals who have difficulty in handing stress and those suffering from behavioral disorders.
Acute low NK cell activity resulting from temporary stress can be eliminated with the elimination of the stress factor. For example, if we are over-tired and under-nourished we can simply rest and eat properly for a few days and recover. However when we become continually immune compromised we start developing recurring problems which may lead into serious or chronic conditions.
NK cell activity level is lowered in times of stress and can become chronically low with chronic stress. Research shows that normal NK cell activity is essential to the recovery and maintenance of good health. One way to offset the effects of stress is to normalize NK cell function.
When the immune system is overwhelmed the communication pathways are compromised and remain compromised until re-established. If the communication networks are not restored there is little opportunity for the immune system to regain full defensive capability.
Communication in the immune system, is accomplished through the cytokine mechanism. These messenger molecules must be activated to energize the communication capability that is necessary for immune system reliability.
Conversely, immune modulation that harnesses the body’s ability to regulate will have an all-encompassing immune response that is not limited to one specific area of immune response. Regulation, upward or downward, in accordance with the needs of the body will be achieved.
Transfer Factor is the ultimate immune system modulator. Research results show transfer factors ability to increase NK Cell activity by 248% over baseline!