4Life Transfer Factor in Physician’s Desk Reference

4Life Transfer Factor Plus is always recommended for use in combination with frequency work as it significantly enhances the immune system and doubles the effectiveness of frequencies. For those with autoimmune disorders regular Transfer Factor is recommended. It is very rare for a supplement to be in the Physicians Desk Reference used by every practicing physician. This is because it works, it’s patented, there are clinical trials, and so forth. Click here if you need some. My spouse hates pills but loves Riovida, a juice with regular transfer factor in it.

4Life Research



4Life Transfer Factor Tri-Factor Formula combines proprietary transfer factors and NanoFactor® molecules extracted from bovine colostrum and chicken egg yolk sources. These molecules contain antigen information which educates, enhances, and helps maintain immune system balance.


Transfer factors are molecules that communicate antigenic immunological information intercellularly and from a donor to a recipient. They support immune function through cell mediated immunity. Transfers factors, which carry antigen specific information to which all tested immune cells respond, are produced by mononuclear cells and serve to support and improve immune function through cell mediated pathways. Mammalian transfer factors, including those of humans are small molecules between 3,500 and 10,000 daltons.[1, 2] Transfer factors are polypeptides that consist of 40 to 44 amino acids [3] and have a conserved region and a variable region. From a molecular biological standpoint, these two properties are analogous to antibodies, however transfer factors’ functions of cell mediated immunity (CMI) and non-specific immunological activity differ almost completely from the functions of antibodies. The molecules that have a molecular weight of less than 3,500 daltons modulate immune response but they do not transfer delayed-type hypersensitivity (DTH).[1]
4Life’s transfer factors are sourced from the ultra-filtration of colostrum and from egg yolks.[4, 5] The molecules obtained from the spray dried ultra-filtrate of bovine colostrum are of two classes; the transfer factors present in the ultra-filtrate of ≤10,000 daltons and the nanofraction molecules that are present in the nano-filtrate of ≤ 3,500 daltons.

Transfer factors were first discovered in 1949 by H. Sherwood Lawrence when he demonstrated that CMI could be transferred from one individual to another by way of low molecular weight extracts of white blood cells. Transfer factors could transfer DTH of a specific form from a skin test positive individual to a skin test negative individual who subsequent to the transfer would skin test positive for that antigen.[6] In a subsequent study in 1955 he demonstrated that DTH could be passed serially, first from a skin test positive individual to a test negative individual, who became test positive, then 6 months later from the second individual to another test negative individual who became test positive.[7] At the time antibodies were the focus of immune research and little was known of the importance of DTH and of the involvement of T-cells in immune response. Transfer factors promote wellness via cell mediated immunity. These compounds are components of colostrum, an infant’s first meal. They bridge the generational gap by passing cell mediated immunity from mother to infant.


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