Sleeping Sickness Frequencies 1.0
Tsetse fly photo from microbewiki.
More than 66 million women, men and children in 36 countries of sub-Saharan Africa suffer from human African trypanosomiasis (HAT). There are two forms of African sleeping sickness, caused by two different parasites:
- Trypanosoma brucei gambiense , which causes a chronic infection lasting years and affecting countries of western and central Africa
- Trypanosoma brucei rhodesiense , which causes acute illness lasting several weeks in countries of eastern and southern Africa
When untreated, trypanosomiasis gives no respite from suffering and ultimately ends in death. The parasite that causes sleeping sickness is called the trypanosome. It is transmitted to humans through the bite of a tsetse fly; of the genusGlossina.
Human trypanosomiasis is therefore a vector-borne parasitic disease. The vector is found only in Africa, between the fifteenth parallels north and south. Its favoured habitat is the vegetation along watercourses and lakes, forest edges and gallery forests, extending to vast areas of scrub savanna. The tsetse fly feeds on the blood of animals and humans. Once inoculated by an infected fly, the trypanosomes proliferate and gradually invade all the organs of the host.
Most of the parasites are effectively destroyed by the host’s natural defences, but some trypanosomes manage to evade the immune system by modifying their surface membrane, a process known as antigenic variation. The trypanosome can express thousands of variants, multiplying with each new surface change.At first, the main clinical signs of human trypanosomiasis are high fever, weakness and headache, joint pains and pruritus (itching). Gradually, the immune defence mechanisms and the patient’s resistance are exhausted.
As the parasite develops in the lymph and blood of the patient, the initial symptoms become more pronounced and other manifestations such as anaemia, cardiovascular and endocrine disorders, abortion, oedema and kidney disorders appear. In advanced stages of disease, the parasite invades the central nervous system. The patient’s behaviour changes; they can no longer concentrate and become indifferent to their environment. Sudden and unpredictable mood changes become increasingly frequent, giving rise to lethargy with bouts of aggressiveness. Patients are overcome by such extreme torpor that eating, speaking, walking or even opening the eyes call for an unsurmountable effort. At night they suffer insomnia and during the day are exhausted by periods of sleep-like unconsciousness. Finally, patients fall into a deep coma and die.
Frequency Foundation has discovered low grade trypanosomiasis infections in the U.S. and Europe. Subscribers have access to frequencies for multiple strains of the parasite and for the wiggleworthia bacterium spread by the tsetse fly and should test themselves for the presence of these organisms.