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Smoking Gun: JAMA Reports Vaccine Seizure Risk Increased for Babies

(NaturalNews) If you choose to have your baby vaccinated with the combination diphtheria, tetanus, whooping cough (pertussis), polio and Haemophilus influenzae type 2 vaccine, a mega-jab collectively known as the DTap-IPV-Hib, your child may be at an increased risk of having a vaccine-induced seizure. A new study published in theJournal of the American Medical Associationhas identified a clear link between the vaccine and the onset of fever-related seizures, which the authors claim will not cause long-term damage.

Yuelian Sun from Aarhus Universityin Denmark and her colleagues evaluated data on roughly 380,000 babies born in Denmark between 2003 and 2008. Children in that country are recommended to get the vaccine at three different times — once when they are three months old, again when they are five months old, and a third time on their first birthday. Upon analysis, the researchers determined that about 7,800 of these children, or just over two percent, had been diagnosed with a fever-related seizure by the time they reach one-and-a-half years old.

The risk of having a fever-related seizure appears to increase after each subsequent jab with the vaccine, and particularly on the same day that it is administered. And yet the study authors and others insist the DTap-IPV-Hib vaccine is safe because such seizures allegedly do not cause brain damage or other permanent harm. Dr. Eugene Shapiro, a pediatrics and infectious diseases researcher atYale University, actually purports that these findings are “reassuring,” and that parents should not be concerned.

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Risk of Febrile Seizures and Epilepsy After Vaccination With Diphtheria, Tetanus, Acellular Pertussis, Inactivated Poliovirus, and Haemophilus Influenzae Type b

  1. Yuelian Sun, PhD
  2. Jakob Christensen, PhD
  3. Anders Hviid, PhD
  4. Jiong Li, PhD;
  5. Peter Vedsted, PhD
  6. Jørn Olsen, PhD
  7. Mogens Vestergaard, PhD
  1. JAMA. 2012;307(8):823831.doi:10.1001/jama.2012.165

  1. Author Affiliations: Department of Public Health (Drs Sun, Li, Olsen, and Vestergaard) and Research Unit for General Practice (Drs Vedsted and Vestergaard), Aarhus University, Aarhus, Denmark; Departments of Neurology and Clinical Pharmacology, Aarhus University Hospital, Aarhus, Denmark (Dr Christensen); Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark (Dr Hviid); and Department of Epidemiology, School of Public Health, University of California, Los Angeles (Dr Olsen).

ABSTRACT

Context Vaccination with whole-cell pertussis vaccine carries an increased risk of febrile seizures, but whether this risk applies to the acellular pertussis vaccine is not known. In Denmark, acellular pertussis vaccine has been included in the combined diphtheria-tetanus toxoids-acellular pertussis–inactivated poliovirus–Haemophilus influenzae type b (DTaP-IPV-Hib) vaccine since September 2002.
Objective To estimate the risk of febrile seizures and epilepsy after DTaP-IPV-Hib vaccination given at 3, 5, and 12 months.
Design, Setting, and Participants A population-based cohort study of 378 834 children who were born in Denmark between January 1, 2003, and December 31, 2008, and followed up through December 31, 2009; and a self-controlled case series (SCCS) study based on children with febrile seizures during follow-up of the cohort.
Main Outcome Measures Hazard ratio (HR) of febrile seizures within 0 to 7 days (0, 1-3, and 4-7 days) after each vaccination and HR of epilepsy after first vaccination in the cohort study. Relative incidence of febrile seizures within 0 to 7 days (0, 1-3, and 4-7 days) after each vaccination in the SCCS study.
Results A total of 7811 children were diagnosed with febrile seizures before 18 months, of whom 17 were diagnosed within 0 to 7 days after the first (incidence rate, 0.8 per 100 000 person-days), 32 children after the second (1.3 per 100 000 person-days), and 201 children after the third (8.5 per 100 000 person-days) vaccinations. Overall, children did not have higher risks of febrile seizures during the 0 to 7 days after the 3 vaccinations vs a reference cohort of children who were not within 0 to 7 days of vaccination. However, a higher risk of febrileseizures was found on the day of the first (HR, 6.02; 95% CI, 2.86-12.65) and on the day of the second (HR, 3.94; 95% CI, 2.18-7.10), but not on the day of the third vaccination (HR, 1.07; 95% CI, 0.73-1.57) vs the reference cohort. On the day of vaccination, 9 children were diagnosed with febrile seizures after the first (5.5 per 100 000 person-days), 12 children after the second (5.7 per 100 000 person-days), and 27 children after the third (13.1 per 100 000 person-days) vaccinations. The relative incidences from the SCCS study design were similar to the cohort study design. Within 7 years of follow-up, 131 unvaccinated children and 2117 vaccinated children were diagnosed with epilepsy, 813 diagnosed between 3 and 15 months (2.4 per 1000 person-years) and 1304 diagnosed later in life (1.3 per 1000 person-years). After vaccination, children had a lower risk of epilepsy between 3 and 15 months (HR, 0.63; 95% CI, 0.50-0.79) and a similar risk for epilepsy later in life (HR, 1.01; 95% CI, 0.66-1.56) vs unvaccinated children.
Conclusions DTaP-IPV-Hib vaccination was associated with an increased risk of febrile seizures on the day of the first 2 vaccinations given at 3 and 5 months, although the absolute risk was small. Vaccination with DTaP-IPV-Hib was not associated with an increased risk of epilepsy.