During my recent visit to Dr. Grossman’s Wellness Center, I asked him what was the most significant advance in antiaging medicine since my last visit six years ago. He said TA-65. Flipping the switch to turn on the genes that extend telomere length is the first “Bridge 2” technology to become available. See Dr. Grossman’s book, “Fantastic Voyage: Live Long Enough to Live Forever.”
TA-65 is expensive but worth it. You can get wholesale pricing from Dale Fawcett <[email protected]>
Nature News 28 Nov 2010
Telomerase reverses ageing process
Dramatic rejuvenation of prematurely aged mice hints at potential therapy.
Protecting chromosome tips doesn’t just prevent ageing. It can reverse it.Peter Lansdorp/Visuals Unlimited/CorbisPremature ageing can be reversed by reactivating an enzyme that protects the tips of chromosomes, a study in mice suggests.
Mice engineered to lack the enzyme, called telomerase, become prematurely decrepit. But they bounced back to health when the enzyme was replaced. The finding, published online today inNature1, hints that some disorders characterized by early ageing could be treated by boosting telomerase activity.
It also offers the possibility that normal human ageing could be slowed by reawakening the enzyme in cells where it has stopped working, says Ronald DePinho, a cancer geneticist at the Dana-Farber Cancer Institute and Harvard Medical School in Boston, Massachusetts, who led the new study. “This has implications for thinking about telomerase as a serious anti-ageing intervention.”
Other scientists, however, point out that mice lacking telomerase are a poor stand-in for the normal ageing process. Moreover, ramping up telomerase in humans could potentially encourage the growth of tumours.